My problems with mattresses are complicated and go back for years. I've tried Select Comfort (which now seems to be Sleep Number), memory foam, and more recently, two different kinds of inner spring with memory foam.
Since around 2008 when the economy went to hell, I started moving around the country essentially "following the money" to keep employed. In each case, mattresses and box springs are two things that hardly ever make the "move across multiple state line" cuts. Too big and bulky to deal with moving. When all this started, I started out buying these high-end memory this, and pillow-top that one-sided type mattresses.
In each case, because of my weight (pre-surgery), memory foam would quickly forget, and pillow-tops would soon compact and form "troughs" in the center of the bed. Nothing like spending $1500 on a bed set to have it turn unusable in 6 months. The manufacturers -- no matter who they were -- always seemed to be able to weasel out of fixing them by claiming one thing or another, so there I was, eating a $1500 investment...
In the end, and with apologies, I can't speak for the latex issue, but what I've found finally works best for me is your average, cheap, flip-able (double-sided), $300 mattress set and a Walmart 4" mattress topper, usually foam or memory foam.. I've had the current set I'm using for the last 5 years that I've been trapped in Virginia and I have to say, I've never had a more comfortable bed. While I've considered replacing the mattress topper (because I've worn out the fabric cover), it's still holding up really well for what has been, in essence, a $400 setup...
Wayne