I think the glasses (on and off at random) and the ketchup comment will be significant. It's looking to me that the writers are going to make it clear they are identical twins. The real Charlie, that's in love with Claire, probably loves ketchup and will be seen drowning his fries in ketchup, which will strike odd for Claire. Real Charlie also doesn't wear glasses, etc. (this is all speculation)
In regards to Kayla, she's grating on my nerves. She's a doctor for Pete's sake, and she knows dang well Sami had twins by two different dads. Just because some of little Henry's dna is "shared" with Tripp only means they are related. It doesn't guarantee he's the dad. Her self righteous angry and rude flip outs is absolutely uncalled for. I'm not happy with the Tripp story at all.